Fuitad and pellechs already mentioned Sheldon: 100% awesomesauce. I would revise that to
Sheldon: 100% pure awesomesauce

or how about
Sheldon: making readers more attractive since 2001

Sheldon: Geek male in your e-mail.

A couple more...

"The billionaire boy: crack business man.
The Talking duck: cracking wise.
The grandpa: showing butt crack.
Sheldon, we'll crack you up."

"An epic tale of love, freindship, nerditry."

The last one should be:

"An epic tale of love, friendship, and nerditry."

how about "One shell of a good time"

Ha! I remembered my password!

Don't know if anyone did this one (got tired of reading the entries, and this one just came to me):

Sheldon: Come for the awesome sauce, stay for the pure ducky goodness.

Wait, this thing isn't over yet, is it?

I'd also like to take this opportunity to beg for a Flaco shirt design. The recent yogi Flaco panel would be perfect! :-)

Like "Seinfeld" without the women, or you know, the copyrighted material.

Sheldon: Not made in France

Sheldon: Now Y3k Compliant!

Sheldon: It's awesome (alternately, "awesomeness guaranteed")

Sheldon: More fun than a box of rocks

Sheldon: Just like you expected, but awesomer

Gotta get this in before someone beats me to it...

The best things in life are squee.

And, of course, you could amend that to "Even when you're a billionaire kid, the best things in life are...squee?

Like the Howard the Duck movie, only with a FUNNY duck.

The story of a boy and his dog, lizard, grampa, duck that talks, and...ah, just read the $#@%& comic already!

The definition of "ducktatstic" (tripple word score)

You Can't spell "sexy" without "Sheldon!"

Sheldon: The Boy, his Gramps, a Duck and his Lizard.

[trying to sound like The Cook, The Thief, His Wife and Her Lover]

Sheldon: Where your best friend is a talking duck!

Sheldon: Where me and my duck drive Gramps crazy!

ooh, even better!

Sheldon: a comic about childhood, family, friendship, and loving the crazy places they take you.

Sheldon: embrace the zany

Sheldon: the story of a ten-year-old billionaire, who lives with his grandfather, pug, lizard, duck who also happens to talk

Sheldon: when life hands you billions you create a talking duck

Ten-year-old billionaire Sheldon lives with his grandfather, pug Oso, lizard Falco and Arthur the talking duck; He even owns Peru.

This one may require a revision from someone else, but it's been stuck in my head:

Sheldon: Fueled by Java

or

Sheldon: Java Fueled!

hrm...I meant coffee, but I just realized it could sound like I mean the programming language...is that good or bad?

My personal favorite description of Sheldon was Merv's, from http://www.unshelved.com 'Sheldon,' he says, 'about a boy and his talking duck.' Dewey answers, 'I'm so glad you finally found a comic for your odd state of mind.'

Sheldon: A boy and his talking duck.

Though I also like Sheldon: Seven Layers of Awesome, which as somebody pointed out on the first page, Dave himself came up with.

maybe...

Sheldon: Even Billionaires have to take out the trash.

Bleh, couldn't remember my old password.

Sheldon: A dork... a duck... a dream...

Sheldon: Who says money can't buy comedy?

Sheldon: It's as funny as you want it to be.

Sheldon: Everybody do the flaco!

Sheldon: Intrigue! Fortune! Danger! A... duck?

Sheldon: when you are confident enough in your own sexuality to be able to handle something a bit 'ducky'

Sheldon: so brilliant you'd think it was from Yorkshire!

Sheldon: Duck soup - without the soup.

Sheldon: Probably the finest boy and duck cartoon strip in the world....

Sheldon: the pekin has landed!

Sheldon: the lizard strikes back!

Sheldon: puts the 'art' in 'cartoon'

Sheldon: funnier than haemorroids.

Sheldon: OK then, funnier than someone else's haemorroids.

Sheldon: Victor Kiam liked it so much he bought the, er, books.

Sheldon: The hafnium rods of the typical modern boy, duck, gramps, pug and lizard nuclear family

Shednol: Even dyslexics enjoy it!

Sheldon: Going quackers on a daily basis

Sheldon: How things probably ought to be. For a given value of 'probably'.

(Of those piled up ahead, I think my vote joins the others for the 100% awesomesauce entry. And nary a hanging chad in sight)

Well here it goes
Sheldon Cruze control for awesome.
Sheldon Your one stop shop for laughs
Sheldon Daily dose of grandure
Sheldon Delusions of gander
that last one works for a book title as well

Sheldon: When life gives you lemons, make lemonade, but when life gives you billions, make a talking duck.