Well, I was going to say Angouleme since I'm planning to go there next year... I don't get the alleged prejudice over strips like yours. It's not like you handle a comic full of All-American dudes in tights saving the world while everything blows up. Why anyone would have issues with Sheldon (or Peanuts, for that matter), I don't know :)
If it were up to me and had mountains of cash, I'd just commit myself to organize a local con in my little corner of the world (Costa Rica) where you could be part of the guests of honor. Nature tours included. But in the meantime, I hope you get better suggestions down this thread.
(I'm going to SPX later this year though. Pity you don't seem to attend)